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Thread: Do you put MSG in your dish?

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[quote=LIONPOWER,36722]MSG is absorbed very quickly (unlike glutamic acid-containing proteins in foods), MSG could spike blood plasma levels of glutamate. Glutamic acid is in a class of chemicals known as excitotoxins, high levels of which have been shown in animal studies to cause damage to areas of the brain unprotected by the blood-brain barrier and that a variety of chronic diseases can arise out of this neurotoxicity. The debate among scientists on the significance of these findings has been raging since the early 1970s, when Dr. John Olney found that high levels of glutamic acid caused damage to the brains of infant mice. The debate is complex and has focused on several areas:
•	Whether the increase in plasma glutamate levels from typical ingestion levels of MSG is enough to cause neurotoxicity in one dose or over time. 
•	Whether humans are susceptible to the neurotoxicity from glutamic acid seen in some animal experiments. It is known that the glutamate ion is important in memory retrieval in humans. 
•	Whether neurotoxicity from excitotoxins is caused by the combined effect of glutamic acid and other excitotoxins such as aspartic acid from aspartame. 
At a meeting of the Society for Neuroscience, the delegates had a split opinion on the issues related to neurotoxic effects from excitotoxic amino acids found in some additives such as MSG.
Some scientists believe that humans and other primates are not as susceptible to excitotoxins as rodents and therefore there is little concern with glutamic acid from MSG. While they agree that the combined effects of all food-based excitotoxins should be considered, their measurements of the blood plasma levels of glutamic acid after ingestion of monosodium glutamate and aspartame demonstrate that there is not a cause for concern.Other scientists feel that primates are susceptible to excitotoxic damageand that humans concentrate excitotoxins in the blood more than other animals. Based on these findings, they feel that humans are approximately 5-6 times more susceptible to the effects of excitotoxins than rodents are. While they agree that typical use of MSG does not spike glutamic acid to extremely high levels in adults, they are particularly concerned with potential effects in infants and young children and the potential long-term neurodegenerative effects of small-to-moderate spikes on plasma excitotoxin levels. 
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